LATEST: Semler Scientific Adds 1,510 Bitcoin in 2025, Total Treasury Hits 3,808 BTC

Semler Scientific has ramped up its bitcoin strategy by increasing its holdings to 3,808 BTC after acquiring 1,510 BTC in 2025 according to its Q1 report. The company’s bitcoin yield stands at 22.2% year to date even as it reported a net loss of $64.7 million for the first quarter. Chairman Eric Semler said the bitcoin treasury continues to grow using operating cash flow and proceeds from financing.

A new public dashboard was launched on the company website to offer real time data on bitcoin metrics including yield and dollar gains. In Q1 the company purchased 894 BTC for $90.7 million and added another 616 BTC through May 12 for $59.6 million. The total fair value of its bitcoin holdings now stands at $387.9 million.

Despite revenue falling to $8.8 million Semler remains confident in its long term vision. CEO Doug Murphy-Chutorian said future growth will come from its cardiovascular product line and bitcoin strategy backed by new financing rounds and investor support.

Source

LATEST: Jack Mallers’ Twenty One Capital Acquires 4,812 Bitcoin for $458 Million

Stablecoin giant Tether has made a major move in the crypto market by purchasing $458.7 million worth of Bitcoin for investment firm Twenty One Capital. The deal involved acquiring 4,812.2 BTC at $95,319 per coin which was then transferred to an escrow wallet on May 9 according to a May 13 SEC filing.

This brings Twenty One’s Bitcoin holdings to 36,312 BTC making it the third-largest corporate holder of Bitcoin. The firm is backed by both Tether and Bitfinex and is preparing to go public through a SPAC merger with Cantor Equity Partners. The company will trade under the ticker XXI once the deal is approved. SoftBank has also backed the firm with a $900 million investment.

Twenty One’s CEO Jack Mallers stated that the firm aims to surpass MicroStrategy as the top Bitcoin-focused investment vehicle. The firm plans to reach 42,000 BTC at launch and focus on Bitcoin per share as its core performance metric instead of earnings.

13 SEC filing

Jack Mallers’ Twenty One Capital And Tether Bought 4,812 Bitcoin For $458,700,000

Today, Cantor Equity Partners, Inc. revealed in a new filing with the SEC that Tether bought 4,812.2 Bitcoin for a total of $458.7 million on behalf of Jack Mallers’ recently launched Bitcoin treasury company, Twenty One Capital, which plans to eventually go public under the ticker $XXI. 

“Pursuant to the Business Combination Agreement, Tether agreed that within ten (10) business days thereof, it would purchase a number of Bitcoin equal to an aggregate purchase price of $458,700,000,” Cantor stated in the filing. “With the Convertible Notes PIPE, entered into on April 22, 2025 by Pubco and the Company with certain investors, less a holdback amount of $52,000,000), and place…

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Semler Scientific Has Purchased 1,510 Bitcoin This Year, Now Holds 3,808 BTC

Semler Scientific (Nasdaq: SMLR) now holds 3,808 BTC after purchasing 1,510 coins since the start of 2025 according to their Q1 earnings report. The growing bitcoin reserve helped generate a 22.2% BTC Yield year to date through May 12, despite a net loss of $64.7 million for the first quarter. 

“We continue to accretively grow our bitcoin arsenal using operating cash flow and proceeds from debt and equity financings,” said Eric Semler, chairman of Semler Scientific. “And we are excited to launch the Semler Scientific dashboard today on our website to provide the public with regularly updated information on our bitcoin holdings and other key metrics.”

Semler has introduced a…

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Why investors should say ‘no’ more often

This is a segment from the Blockworks Daily newsletter. To read full editions, subscribe.

“Half of the troubles of this life can be traced to saying yes too quickly and not saying no soon enough.”

— Josh Billings

If you’ve ever tried meditation, you’ll know that doing nothing for more than about 10 seconds is weirdly difficult.

If you haven’t, you might not realize just how much the human mind rebels against inactivity — an evolutionary inheritance from when doing nothing meant starving on the savannah (or getting eaten), I guess.

These days, our bias for taking action is nowhere more evident than in financial markets, where the headlines are always…

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Crypto players eye more tokenization tests after latest SEC talk

This is a segment from the Forward Guidance newsletter. To read full editions, subscribe.

A day after the SEC’s tokenization-focused roundtable, an asset manager launched its first tokenized fund. We just saw stablecoin-related M&A, too.

First, SEC Chair Paul Atkins reiterated Monday that SEC policymaking “will no longer result from ad hoc enforcement actions.” (Yes, the agency italicized “ad hoc” in the transcript.)

On tokenization, he likened securities moving onchain to the transition of audio recordings from vinyl records to cassette tapes to digital software.

“Blockchain technology holds the promise to allow for a broad swath of novel use cases for…

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Dubai Partners To Accept Bitcoin And Crypto For Government Services

Dubai is officially making Bitcoin a part of everyday life. 

At the Dubai FinTech Summit, the city’s Department of Finance (DOF) signed a Memorandum of Understanding (MoU) with Crypto.com enabling people to use cryptocurrencies such as Bitcoin to pay for government services.

The deal was signed with Dubai officials including His Excellency Abdulla Mohammed Al Basti and His Excellency Abdulrahman Saleh Al Saleh, and was made official by Ahmad Ali Meftah from DOF and Mohammed Al Hakim, President of Crypto.com UAE.

“Dubai continues to advance through coordinated efforts… deploying the latest secure financial technology solutions that support its cashless strategy,” said Al…

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Missouri Bill Would Enable Tax-Free Bitcoin Spending

Missouri’s House Bill 594 (HB594), which would eliminate capital gains taxes for residents in the state, recently passed a vote in the state’s House of Representatives and now awaits a signature from Missouri’s governor, Mike Kehoe (R).

If the bill passes, Missourians can write off “one hundred percent of all income reported as a capital gain for federal income tax purposes,” according to the language in the bill. This means that residents of Missouri would not have to pay a capital gains tax when they spend (or sell) their bitcoin.

Page 1 of HB594

This bill differs from a bill recently introduced in Rhode Island that would permit the state’s residents to spend…

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Public Companies Have Already Bought 3.3x More Bitcoin Than This Year’s New Supply

It’s only May, and public corporations have already bought 3.3 times more Bitcoin than has been supplied in 2025, according to a new graphic from asset manager Bitwise. To put that into perspective, the new supply for the year is around 60,000 BTC, and companies have already surpassed 196,000 BTC in purchases.

*** NOTE: In 2025, public corporations already bought

*checks notes*

3.3 x times the amount of new supply in 2025.

Already exceeds the est. annual supply of 164,250 BTC. pic.twitter.com/raEcbAgtFM

— André Dragosch, PhD⚡ (@Andre_Dragosch) May 13, 2025

A year ago, there were only a few companies, notably Strategy and Metaplanet, holding Bitcoin on their balance sheets. Now…

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‘It’s out of reach of the autocrat’: How Cypherpunk Phil Zimmermann feels about Bitcoin

This is a segment from the Supply Shock newsletter. To read full editions, subscribe.

Money is speech.

Those three words are arguably the most succinct way to express the importance of Bitcoin. 

To the idealist, Bitcoin is an obvious frontier in the war for personal freedoms. It embodies the freedom to transact in the same way that art and newspapers represent freedoms of expression and speech.

Today’s Supply Shock episode features legendary Cypherpunk Phil Zimmermann, the creator of Pretty Good Privacy (PGP) who fought tirelessly for our freedom of digital privacy during the 1990s. Check out one of our previous retrospectives for a primer on Zimmermann.

Who better…

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