Circle and Safe unveiled a strategic partnership aimed at making USDC the default asset for institutional self-custody and onchain treasury operations, the companies said Tuesday. 

The tie-up positions USDC “at the core of the Safe ecosystem,” bundling Circle’s stablecoin infrastructure with Safe’s programmable, multi-sig smart accounts that already see heavy enterprise and DAO usage.

The move lands as Circle leans harder into institutional distribution following its June listing on the New York Stock Exchange under the ticker CRCL.

For Safe, the announcement formalizes an institutional pivot already underway. In June, the Safe Ecosystem Foundation stood up Safe Labs,…

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